Definición de condrodisplasia metafisaria tipo Jansen

Jansen's Metaphyseal Chondrodysplasia or JMC is a disease of the parathyroid hormone receptors. It causes short stature, with normal epiphyseal plates but disorganized metaphyseal regions. más

Jansen's Metaphyseal Chondrodysplasia or JMC is a disease of the parathyroid hormone receptors. It causes short stature, with normal epiphyseal plates but disorganized metaphyseal regions. Hypercalcemia (Elevated levels of calcium in the blood) is often associated with Jansen's, but is not necessarily indicative of JMC. Physical irregularities often associated with Jansen's include: prominent or protruding eyes, a high arched palate, micrognathia or abnormal smallness of the jaws - particularly the lower (mandible) jaw, choanal stenosis, wide cranial sutures and irregular formation of the long bones which can resemble rickets. less